Author Topic: genbank 2020-04-11  (Read 466 times)

gsgs

  • Administrator
  • Full Member
  • *****
  • Posts: 223
    • View Profile
Re: genbank 04/11
« on: April 13, 2020, 02:14:56 am »
above enumeration is wrong, doesn't consider the first digit {expecting only flu-sequences}
it is corrected now in the mutations below




most genomes are from 2 Washington-strains

WA2,101 genomes , 4+2+1 mutations
C00150T{Spain},C02946T{Spain},C14317T{Spain},A23312G{Spain}  , {RI-Feb28}
  G25472T{CA-Feb29}  , C00968T{CA-Feb29}  ,
 (G29462A{WA-Mar13})

WA1,169 genomes , 2+1+2 mutations
C08691T{China},T28053C{China},  {Wuhan,Dec26}
C17969T{WA-Jan19}, 
C17656T{Mar-WA},A17767G{Mar-WA}   {Iran-Feb26}

we had 2 clearly distinguished strains already in Wuhan, Dec.26 .
Once is the predecessor of WA1 and one is the predecessor of WA2

plusminus some contant , the first and last part of the sequences  (~100 nucleotides)
are skipped because they often contain mutations supposed to be sequencing errors

18 genomes that didn't easily align because of insertions or deletions were excluded

there was 1 genome from France, it had a 3bp deletion , none from Germany

----------------------------------------------------
102 German sequences :  https://civnb.info/public/charite-SARS-CoV-2.fasta.gz
@c_drosten  2020/04/13/08:06UTC
https://civnb.info/sequences/

An overview of #SARS-CoV-2 genome sequences from Germany, including early releases by
@charitevirology. Some interesting insights into local clustering and wider dispersal, for
people familiar with German geography.  https://civnb.info/sequences/

102>7+4+87 , >3 different strains
most have C241T,C3037T,A23403G  and most of these also have C14408T

this is WA2 above (add 91)

the one from Jan28 has C241T,C3037T, and A23403G

I assume that was the Webasto-introduction. The whole WA2 and Spain and maybe Italy, France
seems to have descended from it ! (after C14317 was developed in Germany)

WA2,101 genomes , 4+2+1 mutations
C00150T{Spain},C02946T{Spain},C14317T{Spain},A23312G{Spain}  , {RI-Feb28}
  G25472T{CA-Feb29}  , C00968T{CA-Feb29}  ,
 (G29462A{WA-Mar13})
« Last Edit: October 27, 2020, 05:59:06 am by gsgs »