PRRA [nucleotides CTCCTCGGCGGG or TCCTCGGCGGGC, depending how you align ]
is the amino-acid-furin cleavage site ("FCS") inserted into SARS2 at the S1-S2 border in the spike protein.
It is not seen in the similar bat or pangolin viruses, so ir was speculated that it was
inserted in a lab , as done in similar experiments on IBV=infectious bronchitis virus,
a coronavirus in birds, for which they are trying to create chicken-vaccines.
there are 2 such FCS in some coronaviruses :
CTCCTCGGCGGG = insertion
TCTCCTCGGCGGGCACGT , SARS2 , spike , 2038-2055
S P R R A R
AAACCAAGCAAGAGGTCATTTATTGAAGATCTACTTTTC , SARS2,spike,2431-2469
K P S K R S F I E D L L F
AGTCCTAGAAGGCGTTCTTTTATTGAAGACCTTCTATTT , IBV ,spike,2056-2094,AY761141
S P R R R S F I E D L L F
AGTCCTAGAAGGCG
CTCCTCGGCGGG
x----x-xx--x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413309/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832359/pdf/viruses-11-00972.pdf